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13'
This goal: 0–0 → 1–0 · opening goal

Mainz took the lead early at the Opel Arena on the opening matchday of the Bundesliga, 15 August 2021. Moussa Niakhaté struck in the 13th minute to break the deadlock and put 1. FSV Mainz 05 1-0 up against RB Leipzig. It turned out to be the only goal of the afternoon, as the hosts held on for a 1-0 victory. Niakhaté's first-half strike stood as the winner.

Competition
Bundesliga Matchday 1
Date
15 August 2021
Stadium
Opel Arena
Final score
1. FSV Mainz 05 1-0 RB Leipzig
Attendance
10,500