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21'
This goal: 0–0 → 1–0 · opening goal

RB Leipzig hosted 1. FSV Mainz 05 at the Red Bull Arena on Matchday 18 of the Bundesliga, played on 2022-01-08. André Silva broke the deadlock in the 21st minute to put the home side 1-0 up. Leipzig never relinquished that lead, making Silva's first-half strike the winning goal.

Competition
Bundesliga Matchday 18
Date
8 January 2022
Stadium
Red Bull Arena
Final score
RB Leipzig 4-1 1. FSV Mainz 05